Arthritis and interstitial granulomatous dermatitis (Ackerman syndrome) with pulmonary silicosis
Identifieur interne : 002153 ( Main/Exploration ); précédent : 002152; suivant : 002154Arthritis and interstitial granulomatous dermatitis (Ackerman syndrome) with pulmonary silicosis
Auteurs : Stephan Kroesen [Suisse] ; Peter H. Itin [Suisse] ; Paul Hasler [Suisse]Source :
- Seminars in arthritis and rheumatism [ 0049-0172 ] ; 2003.
Descripteurs français
- Pascal (Inist)
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- topic : Association, Adulte.
English descriptors
- KwdEn :
Abstract
Objective: To describe the case of a patient suffering from pulmonary silicosis associated with a rheumatoid factor negative, antinuclear antibody positive, symmetrical, nonerosive synovitis, and interstitial granulomatous dermatitis (IGD) and compare it with similar cases reported in the literature. Methods: Literature search to identify published cases of IGD with arthritis and cases associated with silicosis. Results: Thiry-eight cases of IGD with arthritis were found. These cases were associated with various conditions such as drug reactions, autoimmune diseases, chronic infections, or paraneoplastic syndromes for which no specific underlying cause was identified. The patient had skin lesions corresponding to the rope sign, as noted in other reports. Histology showed a histiocytic, granulomatous dermatitis, which, in association with arthritis, was first described by Ackerman et al. Circulating immune complexes or altered apoptosis have been discussed as mechanisms, although there is no experimental evidence to support either hypothesis. As in other cases, treatment had limited success. Most relief was achieved with hydroxychloroquine, dapsone, and corticosteroids. Conclusions: Arthritis and IGD associated with silicosis is a rare clinical entity that can be differentiated from other conditions. This condition should be considered when patients present with typical dermatologic features, such as the rope sign, and arthritis.
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Arthritis and interstitial granulomatous dermatitis (Ackerman syndrome) with pulmonary silicosis</title><author><name sortKey="Kroesen, Stephan" sort="Kroesen, Stephan" uniqKey="Kroesen S" first="Stephan" last="Kroesen">Stephan Kroesen</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Rheumatologische Universitdtsklinik, Felix Platter Spital</s1><s2>Basel</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Itin, Peter H" sort="Itin, Peter H" uniqKey="Itin P" first="Peter H." last="Itin">Peter H. Itin</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Dermatology, University Hospital</s1><s2>Basel</s2><s3>CHE</s3><sZ>2 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Hasler, Paul" sort="Hasler, Paul" uniqKey="Hasler P" first="Paul" last="Hasler">Paul Hasler</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Rheumatologische Universitdtsklinik, Felix Platter Spital</s1><s2>Basel</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Basel</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">03-0286560</idno><date when="2003">2003</date><idno type="stanalyst">PASCAL 03-0286560 INIST</idno><idno type="RBID">Pascal:03-0286560</idno><idno type="wicri:Area/PascalFrancis/Corpus">000050</idno><idno type="wicri:Area/PascalFrancis/Curation">000016</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000050</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000050</idno><idno type="wicri:doubleKey">0049-0172:2003:Kroesen S:arthritis:and:interstitial</idno><idno type="wicri:Area/Main/Merge">002172</idno><idno type="wicri:Area/Main/Curation">002153</idno><idno type="wicri:Area/Main/Exploration">002153</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Arthritis and interstitial granulomatous dermatitis (Ackerman syndrome) with pulmonary silicosis</title><author><name sortKey="Kroesen, Stephan" sort="Kroesen, Stephan" uniqKey="Kroesen S" first="Stephan" last="Kroesen">Stephan Kroesen</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Rheumatologische Universitdtsklinik, Felix Platter Spital</s1><s2>Basel</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Itin, Peter H" sort="Itin, Peter H" uniqKey="Itin P" first="Peter H." last="Itin">Peter H. Itin</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Dermatology, University Hospital</s1><s2>Basel</s2><s3>CHE</s3><sZ>2 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Hasler, Paul" sort="Hasler, Paul" uniqKey="Hasler P" first="Paul" last="Hasler">Paul Hasler</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Rheumatologische Universitdtsklinik, Felix Platter Spital</s1><s2>Basel</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Basel</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Seminars in arthritis and rheumatism</title><title level="j" type="abbreviated">Semin. arthritis rheum.</title><idno type="ISSN">0049-0172</idno><imprint><date when="2003">2003</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Seminars in arthritis and rheumatism</title><title level="j" type="abbreviated">Semin. arthritis rheum.</title><idno type="ISSN">0049-0172</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Arthritis</term><term>Association</term><term>Case study</term><term>Clinical form</term><term>Dermatitis</term><term>Diagnosis</term><term>Histopathology</term><term>Inflammation</term><term>Lung</term><term>Silicosis</term><term>Treatment</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Silicose</term><term>Poumon</term><term>Association</term><term>Arthrite</term><term>Inflammation</term><term>Forme clinique</term><term>Dermatite</term><term>Histopathologie</term><term>Diagnostic</term><term>Traitement</term><term>Etude cas</term><term>Adulte</term><term>Dermatite granulomateuse interstitielle</term><term>Ackerman syndrome</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Association</term><term>Adulte</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective: To describe the case of a patient suffering from pulmonary silicosis associated with a rheumatoid factor negative, antinuclear antibody positive, symmetrical, nonerosive synovitis, and interstitial granulomatous dermatitis (IGD) and compare it with similar cases reported in the literature. Methods: Literature search to identify published cases of IGD with arthritis and cases associated with silicosis. Results: Thiry-eight cases of IGD with arthritis were found. These cases were associated with various conditions such as drug reactions, autoimmune diseases, chronic infections, or paraneoplastic syndromes for which no specific underlying cause was identified. The patient had skin lesions corresponding to the rope sign, as noted in other reports. Histology showed a histiocytic, granulomatous dermatitis, which, in association with arthritis, was first described by Ackerman et al. Circulating immune complexes or altered apoptosis have been discussed as mechanisms, although there is no experimental evidence to support either hypothesis. As in other cases, treatment had limited success. Most relief was achieved with hydroxychloroquine, dapsone, and corticosteroids. Conclusions: Arthritis and IGD associated with silicosis is a rare clinical entity that can be differentiated from other conditions. This condition should be considered when patients present with typical dermatologic features, such as the rope sign, and arthritis.</div></front></TEI><affiliations><list><country><li>Suisse</li></country></list><tree><country name="Suisse"><noRegion><name sortKey="Kroesen, Stephan" sort="Kroesen, Stephan" uniqKey="Kroesen S" first="Stephan" last="Kroesen">Stephan Kroesen</name></noRegion><name sortKey="Hasler, Paul" sort="Hasler, Paul" uniqKey="Hasler P" first="Paul" last="Hasler">Paul Hasler</name><name sortKey="Itin, Peter H" sort="Itin, Peter H" uniqKey="Itin P" first="Peter H." last="Itin">Peter H. Itin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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